The pH-dependent toxicity of triclosan to five aquatic organisms (Daphnia magna, Photobacterium phosphoreum, Danio rerio, Limnodrilus hoffmeisteri, and Carassius auratus)

Chenguang Li, Ruijuan Qu, Jing Chen, Shuo Zhang, Ahmed A. Allam, Jamaan Ajarem, Zunyao Wang

Research output: Contribution to journalJournal articlepeer-review

22 Scopus citations

Abstract

Triclosan (TCS) is an antibacterial and antifungal agent widely used in personal care products, and it has been frequently detected in the aquatic environment. In the present study, the acute toxicity of TCS to Daphnia magna, Photobacterium phosphoreum, Danio rerio, and Limnodrilus hoffmeisteri was assessed under different pH conditions. Generally, TCS was more toxic to the four aquatic organisms in acidic medium. The LC50 values for D. magna and D. rerio were smaller among the selected species, suggesting that D. magna and D. rerio were more sensitive to TCS. In addition, the oxidative stress-inducing potential of TCS was evaluated in Carassius auratus at three pH values. Changes of superoxide dismutase (SOD) and catalase (CAT) activity, glutathione (GSH) level, and malondialdehyde (MDA) content were commonly observed in all TCS exposure groups, indicating the occurrence of oxidative stress in the liver of C. auratus. The integrated biomarker response (IBR) index revealed that a high concentration of TCS induced great oxidative stress in goldfish under acidic condition. This work supplements the presently available data on the toxicity data of TCS, which would provide some useful information for the environmental risk assessment of this compound.

Original languageEnglish
Pages (from-to)9636-9646
Number of pages11
JournalEnvironmental Science and Pollution Research
Volume25
Issue number10
DOIs
StatePublished - 1 Apr 2018

Keywords

  • Acute toxicity
  • Aquatic organisms
  • Oxidative stress
  • pH effects
  • Triclosan

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