Molecular modeling, spectral, and biological studies of 4-formylpyridine-4 N-(2-pyridyl) thiosemicarbazone (HFPTS) and its Mn(II), Fe(III), Co(II), Ni(II), Cu(II), Cd(II), Hg(II), and UO2(II) complexes

Nashwa M. El Metwally, Reem Arafa, Usama El-Ayaan

Research output: Contribution to journalJournal articlepeer-review

20 Scopus citations

Abstract

The present work describes the preparation and characterization of some metal ion complexes derived from 4-formylpyridine-4 N-(2-pyridyl)thiosemicarbazone (HFPTS). The complexes have the formula; [Cd(HFPTS)2H2O]Cl2, [CoCl2(HPTS)] ·H2O, [Cu2Cl4(HPTS)]·H 2O, [Fe (HPTS)2Cl2]Cl·3H2O, [Hg(HPTS)Cl2]·4H2O, [Mn(HPTS)Cl2] ·5H2O, [Ni(HPTS)Cl2]·2H2O, [UO2(FPTS)2(H2O)]·3H2O. The complexes were characterized by elemental analysis, spectral (IR, 1H-NMR and UV-Vis), thermal and magnetic moment measurements. The neutral bidentate coordination mode is major for the most investigated complexes. A mononegative bidentate for UO2(II), and neutral tridentate for Cu(II). The tetrahedral arrangement is proposed for most investigated complexes. The biological investigation displays the toxic activity of Hg(II) and UO2(II) complexes, whereas the ligand displays the lowest inhibition activity toward the most investigated microorganisms.

Original languageEnglish
Pages (from-to)2357-2367
Number of pages11
JournalJournal of Thermal Analysis and Calorimetry
Volume115
Issue number3
DOIs
StatePublished - Mar 2014
Externally publishedYes

Keywords

  • Biological studies
  • Modeling
  • Spectral
  • Thiosemicarbazone complexes

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