Malocclusion and genetics

Shifat A. Nowrin, Sanjida Haque, Mohammad Khursheed Alam

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Because of the presumption that malocclusions with a genetic cause are less amendable to treatment than those with an environmental cause, some investigators and clinicians would like a definite answer to the question of whether a patient's malocclusion is the result of genetic or environmental factors. However, the pattern of growth and development is typically the result of an interaction between multiple genetic and environmental factors over time. Malocclusions are not influenced severely by a single gene [17]. Even for monogenic traits and syndromes, evidence exists for the influence of other genes and environmental factors. Genetic investigation could be a future diagnostic tools for better treatment outcome. Moreover, individual genetic variation has specific role in response to treatment, which is directed to a specific environmental change. In conclusion, genetic analysis is an important tool in clinical orthodontics. The etiological diversity is the main complicating factor for treatment and diagnosis in various types of malocclusions. The main aim of this chapter is to highlight the genetic background in terms of different malocclusion.

Original languageEnglish
Title of host publicationMalocclusion
Subtitle of host publicationCauses, Complications and Treatment
PublisherNova Science Publishers, Inc.
Number of pages16
ISBN (Electronic)9781536131246
ISBN (Print)9781536131239
StatePublished - 1 Jan 2018


  • Gene
  • Genetic effects
  • Malocclusion


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