Histopathological analysis of 2,4,5-trinitrobenzene sulphonic acid (TNBS)-induced mouse colitis

Kang Ho Choi, Hong Hyeonju, Irfan A. Rather

Research output: Contribution to journalJournal articlepeer-review


Ulcerative colitis is one of the chronic diseases that results in inflammation of colon in humans. In this Visual experiment we demonstrate the histopathology of TNBS induced colitis model of mouse. The experiment involves following steps: a) Selection of mouse model, b) Induction of colitis, c) Paraffin sectioning of colon tissue, d) Hematoxylin and Eosin staining, and d) Microscopic observation.

Original languageEnglish
Pages (from-to)610-614
Number of pages5
JournalBangladesh Journal of Pharmacology
Issue number3
StatePublished - 2016
Externally publishedYes


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