Cancer targeting potential of bioinspired chain like magnetite (Fe3O4) nanostructures

S. Swathi, Fuad Ameen, G. Ravi, R. Yuvakkumar, S. I. Hong, Dhayalan Velauthapillai, Muneera D.F. AlKahtani, M. Thambidurai, Cuong Dang

Research output: Contribution to journalJournal articlepeer-review

3 Scopus citations


Iron is significant, earth abundant and inexpensive materials in everyday use. Non toxicity and clean manufacturing process is still a challenging role in scientific world. The chain like Fe3O4 nanostructures were synthesized using the mixtures such as iron nitrate and Rambutan. Magnetite Fe3O4 was verified using X-ray powder diffraction (XRD). Metal oxide (Fe–O) and A1g and Eg phonon modes are substantiated employing Fourier-transform infrared spectroscopy (FTIR) and Raman spectra. A product chemical state was investigated by high resolution X-ray photoelectron spectroscopy (XPS) spectra. Chain like morphology and polycrystalline nature is attributed by transmission electron microscopy (TEM) analysis. Weight loss activity was revealed through thermogravimetric analysis (TGA) analysis. In application studies, higher concentration of Fe3O4 nanostructures was more effective than the low concentration. Moreover, cytotoxicity effects and cell viability on human cancer cell lines were observed and tested for cancer treatment.

Original languageEnglish
Pages (from-to)982-987
Number of pages6
JournalCurrent Applied Physics
Issue number8
StatePublished - Aug 2020


  • Cell viability
  • Chain like morphology
  • FeO


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